NCCN Guidelines for Patients® | Chronic Myeloid Leukemia

15 NCCN Guidelines for Patients ® : Chronic Myeloid Leukemia, 2018 Blood tests Blood tests are useful for diagnosing CML. They can help to find other diseases, too. They require a sample of your blood. Samples of blood can be removed with a blood draw. Blood draw Before a blood draw, you might need to stop drinking and eating for several hours. A needle will be inserted into your vein to remove blood. Your blood sample will be sent to a lab. A pathologist will perform the blood tests. A pathologist is a doctor who’s an expert in testing cells to find disease. CBC with differential A CBC ( c omplete b lood c ount) measures parts of the blood. It is often done with a machine. Test results include counts of white blood cells, red blood cells, and platelets. Your blood counts may be low or high because of cancer or another health problem. It is an essential test that gives a picture of your overall health. There are several types of white blood cells. A differential counts the number of each type of cell. It also checks if the counts are in balance with each other. Your doctor can determine the cause of an abnormal white blood count from this test. Chemistry profile Chemicals in your blood come from your liver, bone, and other organs. A chemistry profile measures the levels of these chemicals. Abnormal results may be a sign that an organ or body system isn’t working well. Such organs include your liver and kidneys. This test may be repeated during and after treatment to assess results. 2 Testing for CML Blood tests Guide 1. Tests for CML Test name • Medical history • Physical exam • CBC with differential • Chemistry profile • Bone marrow aspiration and biopsy • Cytogenetics for Philadelphia chromosome • QPCR for BCR-ABL1 gene • Hepatitis panel

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