NCCN Guidelines for Patients® | Chronic Myeloid Leukemia

16 NCCN Guidelines for Patients ® : Chronic Myeloid Leukemia, 2018 2 Testing for CML Bone marrow exam Bone marrow exam A bone marrow exam removes cells from your bones for testing. Test results will be used to confirm the disease phase. A bone marrow exam may also be done during treatment to check results. Aspiration and biopsy A bone marrow exam consists of two procedures. A bone marrow aspiration removes a small amount of liquid bone marrow. A bone marrow biopsy removes a sample of bone and soft bone marrow. Often, these procedures are done at the same time. They are performed on the back of the hip bone. You may receive a light sedative beforehand. You will likely lie on your side as shown in Figure 5 . Some people lie on their belly. Your doctor will first clean and numb your skin. For aspiration, a hollow needle will be inserted into your skin and pushed into the bone. Liquid bone marrow will then be drawn into a syringe. For the biopsy, a wider needle will be inserted into your bone and rotated to remove a core sample. You may feel bone pain during and after the procedures for a few days. Your skin may bruise. Lab tests The samples will be sent to a lab for testing. A pathologist will study the samples with a microscope. He or she will assess the number of cells and how they look. This information is used to determine the CML phase. Genetic tests will also be done. Figure 5 Bone marrow exam A bone marrow exam removes a sample of bone and marrow for testing. The procedure is often done on the back of the hip. Illustration Copyright © 2017 Nucleus Medical Media, All rights reserved.