NCCN Guidelines for Patients® | Chronic Myeloid Leukemia

39 NCCN Guidelines for Patients ® : Chronic Myeloid Leukemia, 2018 5 Advanced phases Review Review † † Additional testing is needed for advanced phases to plan the best treatment. † † Treatment options are based on prior treatment, mutations in CML cells, and your health. Joining a clinical trial is encouraged. † † TKIs are often used to treat the advanced phase. Chemotherapy or steroids may be added if in blast phase. † † Some people may receive an allogeneic HCT. If there is a big drop in CML cells, think about taking a TKI for 1 year. If CML cells remain high or increase, talk with your transplant doctor about treatment options.