NCCN Guidelines for Patients® | Chronic Myeloid Leukemia

49 NCCN Guidelines for Patients ® : Chronic Myeloid Leukemia, 2018 Dictionary Dictionary accelerated phase The second phase of chronic myelogenous leukemia progression, when the number of blast cells is increased. acute lymphoblastic leukemia (ALL) A fast-growing cancer that causes too many immature white blood cells called lymphoblasts to be made. acute myeloid leukemia (AML) A fast-growing cancer that causes too many immature white blood cells called myeloblasts to be made. adherence The extent to which you take your medicine the right way, as explained by your doctor. advanced phase A rating of chronic myelogenous leukemia, when the number of immature blood cells (blast cells) is high and it is causing symptoms. allogeneic hematopoietic cell transplant (HCT) A treatment in which the patient receives healthy, immature blood-forming cells from another person to replace damaged or diseased cells in the bone marrow. Also called allogeneic stem cell transplant. anemia A health condition in which the number of red blood cells is low. basophil A type of white blood cell that helps fight infections and has small particles (granules). BCR-ABL1 gene An abnormal gene that is formed when the BCR gene and ABL gene join together on the Philadelphia chromosome. Also called BCR-ABL1 fusion gene. BCR-ABL1 protein An abnormal protein that is made by the BCR-ABL1 fusion gene and causes too many abnormal white blood cells to be made. blast cell An immature blood cell. blast phase The final phase of chronic myelogenous leukemia, which has the highest number of blast cells in the blood and bone marrow and can be life-threatening. Also called blast crisis. blood chemistry profile A test that measures the amounts of many different chemicals in a sample of blood. blood stem cell An immature blood-forming cell from which all other types of blood cells are made. Also called hematopoietic stem cell. bone marrow The soft, sponge-like tissue in the center of most bones where blood cells are made. bone marrow aspiration The removal of a small amount of liquid bone marrow to test for disease. bone marrow biopsy The removal of a small amount of solid bone and bone marrow to test for disease. bone marrow cytogenetics Test of a sample of bone marrow to look for changes in the cells’ chromosomes. chemotherapy (chemo) Drugs that kill fast-growing cells, including cancer cells and normal cells. chromosomes Long strands that contain bundles of coded instructions in cells for making and controlling cells. chronic myelogenous leukemia (CML) A slow-growing cancer that starts in the bone marrow and causes too many granulocytes to form. chronic phase The first phase of chronic myelogenous leukemia, when the number of white blood cells is higher than normal but may not cause symptoms. clinical trial Research on a test or treatment to assess its safety or how well it works.

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