NCCN Guidelines for Patients® | Chronic Myeloid Leukemia

Contents 7
How to use this book 8
1 CML basics 9
Blood 10
A disease of cells 12
Three phases 13
Review 14
2 Testing for CML 15
Medical history 16
Physical exam 16
Blood tests 17
Bone marrow exam 18
Genetic tests 19
Hepatitis panel 20
Review 20
3 Overview of cancer treatments 21
Tyrosine kinase inhibitors 22
Chemotherapy 24
Hematopoietic cell transplant 26
Clinical trials 27
Review 28
4 Treatment guide: Chronic phase 29
Risk groups 30
First-line treatment 30
Monitoring 31
Second-line treatment 33
Review 34
5 Treatment guide: Advanced phases 35
Additional testing 36
Treatment 38
HCT follow-up treatment 40
Review 41
6 Making treatment decisions 42
It’s your choice 43
Questions to ask your doctors 43
What’s my diagnosis and prognosis? 44
What are my options? 45
What does each option require of me? 46
What is your experience? 47
Deciding between options 48
Websites 49
Review 49
Glossary 50
Dictionary 51
Acronyms 55
NCCN Panel Members for Chronic Myeloid Leukemia 58
NCCN Member Institutions 59
Index 60

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