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NCCN Guidelines for Patients


Esophageal Cancer, Version 1.2016

Return of cancer

Guide 11. Treatment by cancer site

Site of cancer

Prior treatment

What are the options?

Locoregional recurrence

(M0 score)

You had an esophagectomy

but not chemoradiation

• Chemoradiation,

• Surgery,

• Chemotherapy, or

• Supportive care

You had chemoradiation but

not an esophagectomy

• Esophagectomy if able to have surgery, or

• Supportive care if unable to have surgery

Metastatic recurrence

(M1 score)


• Supportive care


Treatment guide: Squamous cell carcinoma Return of cancer