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62

NCCN Guidelines for Patients

®

Esophageal Cancer, Version 1.2016

5

Treatment guide: Squamous cell carcinoma Advanced cancer

Guide 13. First-line systemic treatment

Preferred regimens

Other regimens

Fluoropyrimidine (5-FU or capecitabine), cisplatin

Paclitaxel with cisplatin or carboplatin

Fluoropyrimidine (5-FU or capecitabine), oxaliplatin Docetaxel with cisplatin

Docetaxel, cisplatin, 5-FU

Fluoropyrimidine (5-FU or capecitabine)

Docetaxel, oxaliplatin, 5-FU

Docetaxel

Docetaxel, carboplatin, 5-FU

Paclitaxel

Fluorouracil, irinotecan

Epirubicin, cisplatin, 5-FU

Epirubicin, oxaliplatin, 5-FU

Epirubicin, cisplatin, capecitabine

Epirubicin, oxaliplatin, capecitabine

Guide 14. Second-line systemic treatments

Preferred regimens

Other regimens

Docetaxel

Irinotecan, cisplatin

Paclitaxel

Irinotecan, fluoropyrimidine (5-FU or capecitabine)

Irinotecan

Docetaxel and irinotecan