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28

NCCN Guidelines for Patients

®

Hodgkin Lymphoma, Version 1.2015

3

Overview of cancer treatments Stem cell transplant

and feel painful when touched. You may also have

short-term hair loss, but only where treated.

Treatment to the head and neck can cause mouth

sores, dry mouth, changes in taste, and a sore throat.

Chest radiation can cause a dry cough or a sensation

of a lump when you swallow. Radiation near your belly

can cause nausea and maybe vomiting, and when

given between your hip bones, diarrhea and cramps.

Late side effects of radiation may also occur. Again,

the effects depend on the treatment site. Examples

include dry mouth, dental cavities, hypothyroidism;

lung scarring, heart disease, infertility, and second

cancers.

Not all side effects of radiation are listed here.

Please ask your treatment team for a complete list of

common and rare side effects. If a side effect bothers

you, tell your treatment team. There may be ways to

help you feel better. There are also ways to prevent

some side effects.

Stem cell transplant

Blood stem cells are cells that develop into mature

blood cells. Stem cells and mature blood cells

are made in bone marrow. The goal of a stem cell

transplant is to cure cancer by replacing unhealthy

blood stem cells with healthy ones. This is done

by destroying bone marrow with high doses of

chemotherapy then transplanting healthy blood stem

cells. The healthy blood stem cells form new marrow

and blood cells.

A stem cell transplant is not first used to treat

Hodgkin lymphoma. It is an option if you need more

treatment after first-time treatment. Autologous stem

cell transplant is almost always used for Hodgkin

lymphoma. This type of transplant uses your own

stem cells. This treatment is also called HDT/

ASCR (

h

igh-

d

ose

t

herapy with

a

utologous

s

tem

c

ell

r

escue).

Using stem cells from a donor is called an allogeneic

stem cell transplant. This method may be an option

for some people but more research is needed.

The steps of treatment with autologous stem cell

transplant are described next.

Collecting stem cells

The first step of a stem cell transplant is to collect, or

harvest, your blood stem cells. Blood stem cells can

be collected from either your blood or bone marrow. If

collected from your blood, a process called apheresis

will be done.

For apheresis, you first may be given medicine to

increase the number of stem cells in blood. Then,

your blood will be removed from a large vein most

likely in your arm. It will flow through a tube and into

a machine that removes stem cells. The rest of your

blood will be returned to you in your other arm.