NCCN Guidelines for Patients
Hodgkin Lymphoma, Version 1.2015
Overview of cancer treatments Stem cell transplant
and feel painful when touched. You may also have
short-term hair loss, but only where treated.
Treatment to the head and neck can cause mouth
sores, dry mouth, changes in taste, and a sore throat.
Chest radiation can cause a dry cough or a sensation
of a lump when you swallow. Radiation near your belly
can cause nausea and maybe vomiting, and when
given between your hip bones, diarrhea and cramps.
Late side effects of radiation may also occur. Again,
the effects depend on the treatment site. Examples
include dry mouth, dental cavities, hypothyroidism;
lung scarring, heart disease, infertility, and second
Not all side effects of radiation are listed here.
Please ask your treatment team for a complete list of
common and rare side effects. If a side effect bothers
you, tell your treatment team. There may be ways to
help you feel better. There are also ways to prevent
some side effects.
Stem cell transplant
Blood stem cells are cells that develop into mature
blood cells. Stem cells and mature blood cells
are made in bone marrow. The goal of a stem cell
transplant is to cure cancer by replacing unhealthy
blood stem cells with healthy ones. This is done
by destroying bone marrow with high doses of
chemotherapy then transplanting healthy blood stem
cells. The healthy blood stem cells form new marrow
and blood cells.
A stem cell transplant is not first used to treat
Hodgkin lymphoma. It is an option if you need more
treatment after first-time treatment. Autologous stem
cell transplant is almost always used for Hodgkin
lymphoma. This type of transplant uses your own
stem cells. This treatment is also called HDT/
Using stem cells from a donor is called an allogeneic
stem cell transplant. This method may be an option
for some people but more research is needed.
The steps of treatment with autologous stem cell
transplant are described next.
Collecting stem cells
The first step of a stem cell transplant is to collect, or
harvest, your blood stem cells. Blood stem cells can
be collected from either your blood or bone marrow. If
collected from your blood, a process called apheresis
will be done.
For apheresis, you first may be given medicine to
increase the number of stem cells in blood. Then,
your blood will be removed from a large vein most
likely in your arm. It will flow through a tube and into
a machine that removes stem cells. The rest of your
blood will be returned to you in your other arm.