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46

NCCN Guidelines for Patients

®

Hodgkin Lymphoma, Version 1.2015

4.3 Treatment for refractory cancer

4

Treatment guide: Classical Hodgkin lymphoma Treatment for refractory disease

Chart 4.3 Treatment path

Treatment

Test results

Treatment

Maintenance

Treatment

appears to be

working well

Chemotherapy

or brentuximab

vedotin

Brentuximab vedotin

for 1 year if primary

refractory disease

Stem cell transplant ±

radiation therapy

Radiation therapy

Observation

Treatment

may be

working poorly

Radiation therapy

More cancer drugs ±

radiation therapy

Treatment

appears to be

working less

than wanted

Radiation therapy

More cancer drugs ±

radiation therapy

Brentuximab vedotin

for 1 year if primary

refractory disease

Stem cell transplant ±

radiation therapy