NCCN Guidelines for Patients
Hodgkin Lymphoma, Version 1.2015
Treatment guide: Classical Hodgkin lymphoma Review
• First-time treatment for classic Hodgkin
lymphoma almost always consists of
chemotherapy and radiation therapy.
Sometimes, chemotherapy alone is given if it
works really well. More chemotherapy is given
to cancers that are larger or more widespread.
• Refractory cancer is cancer that isn’t cured
during first-time treatment. Chemotherapy is
often first used for treatment. If the cancer
responds well, you may have a stem cell
transplant with or without radiation therapy.
If the cancer responds less well, you may
receive other drug treatments with or without
radiation therapy. Radiation therapy alone
is also an option to treat refractory disease
• A relapse is cancer that re-appears on tests
after a cancer-free period. Treatment options
for stage IA or IIA depend on whether you had
radiation therapy before. If not, chemotherapy
with or without stem cell transplant, radiation
therapy, or both is often first used. For some
people, radiation therapy alone may be first
used. Treatment for all other relapsed cancers
is like treatment for refractory disease.
• Follow-up care is given when there are no
signs of cancer after treatment. Follow-up
care includes tests that check for signs of
cancer and side effects of cancer treatment. It
also includes treatment that prevents disease.