NCCN Guidelines for Patients
Hodgkin Lymphoma, Version 1.2015
Stage I and II cancers have grown either above or
below your diaphragm. The cancer is not on both
sides. Stage IA and IIA cancers haven’t caused
B symptoms (fevers, night sweats, weight loss).
Treatment options for stage IA and IIA are based
on whether the cancer is large (“bulky.”) There are
two groups of bulky cancers. The first group is large
tumors that occur between the lungs. Large tumors
are those that have an MMR (
greater than 0.33. The second group is large tumors
in lymph nodes. These tumors are large when they
are 10 cm or greater in width.
maps the treatment path for non-bulky
stage IA or IIA cancers. Radiation therapy is the
preferred treatment choice. If you have stage IA,
starting follow-up care is an option if the tumor was
fully removed during biopsy. Read Part 5.4 for more
information on follow-up care.
After radiation therapy, follow-up care can be started
if there are no signs of cancer. If there are signs of
cancer, a biopsy is needed. If no cancer is found, you
can start follow-up care. If cancer is found, read Part
5.3 to learn which treatments you can receive next.
maps a treatment path for all other
stage I and II cancers. Treatment begins with
chemotherapy and radiation therapy. Rituximab may
be added. Chemotherapy may be ABVD, CHOP, or
CVP. These combination regimens consist of:
is doxorubicin, bleomycin, vinblastine,
is cyclophosphamide, doxorubicin,
is cyclophosphamide, vincristine,
After treatment, follow-up care can be started if there
are no signs of cancer. If there are signs of cancer, a
biopsy is needed. If no cancer is found, you can start
follow-up care. If cancer is found, read Part 5.3 to
learn which treatments you can receive next.
Treatment guide: Nodular lymphocyte-
predominant Hodgkin lymphoma
Stages I and II treatment