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59

NCCN Guidelines for Patients

®

Hodgkin Lymphoma, Version 1.2015

Stage I and II cancers have grown either above or

below your diaphragm. The cancer is not on both

sides. Stage IA and IIA cancers haven’t caused

B symptoms (fevers, night sweats, weight loss).

Treatment options for stage IA and IIA are based

on whether the cancer is large (“bulky.”) There are

two groups of bulky cancers. The first group is large

tumors that occur between the lungs. Large tumors

are those that have an MMR (

m

ediastinal

m

ass

r

atio)

greater than 0.33. The second group is large tumors

in lymph nodes. These tumors are large when they

are 10 cm or greater in width.

Chart 5.1.1

maps the treatment path for non-bulky

stage IA or IIA cancers. Radiation therapy is the

preferred treatment choice. If you have stage IA,

starting follow-up care is an option if the tumor was

fully removed during biopsy. Read Part 5.4 for more

information on follow-up care.

After radiation therapy, follow-up care can be started

if there are no signs of cancer. If there are signs of

cancer, a biopsy is needed. If no cancer is found, you

can start follow-up care. If cancer is found, read Part

5.3 to learn which treatments you can receive next.

Chart 5.1.2

maps a treatment path for all other

stage I and II cancers. Treatment begins with

chemotherapy and radiation therapy. Rituximab may

be added. Chemotherapy may be ABVD, CHOP, or

CVP. These combination regimens consist of:

ABVD

is doxorubicin, bleomycin, vinblastine,

dacarbazine.

CHOP

is cyclophosphamide, doxorubicin,

vincristine, prednisone.

CVP

is cyclophosphamide, vincristine,

prednisone.

After treatment, follow-up care can be started if there

are no signs of cancer. If there are signs of cancer, a

biopsy is needed. If no cancer is found, you can start

follow-up care. If cancer is found, read Part 5.3 to

learn which treatments you can receive next.

5

Treatment guide: Nodular lymphocyte-

predominant Hodgkin lymphoma

Stages I and II treatment