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61

NCCN Guidelines for Patients

®

Hodgkin Lymphoma, Version 1.2015

Chemotherapy is often used to treat stages III and IV.

Chemotherapy may be ABVD, CHOP, or CVP. These

combination regimens consist of:

ABVD

is doxorubicin, bleomycin, vinblastine,

dacarbazine.

CHOP

is cyclophosphamide, doxorubicin,

vincristine, prednisone.

CVP

is cyclophosphamide, vincristine,

prednisone.

Chart 5.2.1

maps a treatment path for stage IIIA

or IVA cancers. These cancers haven’t caused

B symptoms (fevers, night sweats, weight loss).

There are three options to first-time treatment.

Chemotherapy is one option. Radiation therapy,

rituximab, or both may be added. The second option

is radiation therapy to the cancer site to relieve

symptoms. The goal is not to cure the cancer. The

third option is to take rituximab.

If the cancer responds to these treatments, follow-

up care can be started or you may have radiation

therapy. Radiation therapy is only an option if you

haven’t had it before.

If the cancer is the same or a larger size, a biopsy is

needed. If no cancer is found, you can start follow-up

care. Read Part 5.4 for more information. If cancer

is found, read Part 5.3 to learn which treatments you

can receive next.

Chart 5.2.2

maps a treatment path for stage IIIB or

IVB cancers. Treatment begins with chemotherapy.

Radiation therapy, rituximab, or both may be added.

If the cancer shrinks, follow-up care can be started. A

second option is radiation therapy. It is only an option

if you haven’t had it before.

If the cancer is the same or a larger size, a biopsy is

needed. If no cancer is found, you can start follow-up

care. Read Part 5.4 for more information. If cancer

is found, read Part 5.3 to learn which treatments you

can receive next.

5

Treatment guide: Nodular lymphocyte-

predominant Hodgkin lymphoma

Stages III and IV treatment