NCCN Guidelines for Patients
Hodgkin Lymphoma, Version 1.2015
Treatments for Hodgkin lymphomas don’t always
work the first time. Cancer may also re-appear after
a cancer-free time period. In both cases, a biopsy is
needed to confirm that cancer is present. If it is, the
type of cancer will also be assessed.
If no cancer is found, ongoing follow-up care is
advised. Read Part 5.4 for more information.
Likewise, if cancer is found but not causing
symptoms, follow-up care is advised. Some cancers
do not grow fast and will not need treatment.
Sometimes Hodgkin lymphoma transforms into a fast-
growing non-Hodgkin’s lymphoma. There are
Guidelines for Patients
for specific types of non-
Hodgkin lymphoma. If available, read the one that
pertains to the new type of cancer you have.
maps a treatment path for refractory
or relapsed cancer that is causing symptoms.
Treatment begins with rituximab. Chemotherapy,
radiation therapy, or both may be added. Approved
chemotherapy regimens include:
(cyclophosphamide, vincristine, procarbazine,
(dexamethasone, cisplatin, high-dose
(etoposide, methylprednisolone, high-dose
cytarabine and cisplatin),
(gemcitabine, carboplatin, dexamethasone),
(gemcitabine, vinorelbine, liposomal
(ifosfamide, carboplatin, etoposide),
(ifosfamide, gemcitabine, vinorelbine),
(carmustine, cytarabine, etoposide,
(etoposide, ifosfamide, mesna, mitoxantrone).
If treatment shrinks the cancer, follow-up care can be
started when cancer symptoms stop. Read Part 5.4
for more information. If the cancer is the same or a
larger size, a biopsy is needed.
Treatment guide: Nodular lymphocyte-
predominant Hodgkin lymphoma
Treatment for refractory or relapsed cancer