NCCN Guidelines for Patients
Hodgkin Lymphoma, Version 1.2015
• First-time treatment for stage IA or IIA cancers
depends on if the cancer is large (bulky).
Most small cancers are treated with radiation
therapy. All other stage I and II cancers are
treated with chemotherapy and radiation
therapy. Rituximab may be added.
• Stage III and IV cancers are often treated with
chemotherapy. Radiation therapy, rituximab,
or both may be added. Stage IIIA and IVA may
be treated with radiation therapy or rituximab
• Refractory cancer is cancer that isn’t cured
during first-time treatment. Relapse is cancer
that re-appears on tests after a cancer-free
period. Refractory or relapsed cancers that
are causing symptoms may be treated with
rituximab. Chemotherapy, radiation therapy, or
both may be added.
• Follow-up care is given when there are no
signs of cancer after treatment. Follow-up
care includes tests that check for signs of
cancer and side effects of cancer treatment. It
also includes treatment that prevents disease.
Treatment guide: Nodular lymphocyte-
predominant Hodgkin lymphoma