NCCN Guidelines for Patients® | Lung Cancer - Non-Small Cell Lung Cancer

48 NCCN Guidelines for Patients ® : Lung Cancer – Non-Small Cell, 2018 Regimens Chemotherapy drugs used for lung cancer are listed in Guide 5 . Sometimes, only one drug is used. Other times, more than one drug is used because drugs differ in the way they work.. Often, cisplatin or carboplatin—drugs made with platinum—is used with another drug. These regimens are called platinum- doublet chemotherapy. Parts 6 and 7 are guides that explain who should receive which treatments. What to expect A member of your treatment team will likely review what to expect with you. Drugs can differ in terms of how they are given. Ask your treatment team how you should prepare for treatment. Most chemotherapy drugs for lung cancer are liquids that are slowly injected into a vein. Some are a pill that is swallowed. By any method, the drugs travel in your bloodstream to treat cancer throughout your body. Doctors use the term “systemic” when talking about a cancer treatment for the whole body. Chemotherapy is given in cycles of treatment days followed by days of rest. The cycles vary in length depending on which drugs are used. Common cycles are 14, 21, or 28 days long. Giving chemotherapy in cycles gives your body a chance to recover after receiving chemotherapy. If you will have chemotherapy, ask your doctor how many cycles and days of treatment there are within a cycle. Side effects Side effects from chemotherapy differ among people. Some people have many side effects. Other people have few. Some side effects can be very serious. Others can be unpleasant but not serious. Side effects of chemotherapy depend on multiple factors. These factors include the drug type, amount taken, length of treatment, and the person. In general, side effects are caused by the death of fast- growing cells. Fast-growing cells are found in the hair follicles, gut, mouth, and blood. Death of these cells can cause 5 Overview of cancer treatments Chemotherapy Guide 5. Chemotherapy Generic (chemical) name Brand name (sold as) Carboplatin – Cisplatin Platinol ® Docetaxel Taxotere ® Etoposide; Etoposide phosphate Etopophos ® Gemcitabine hydrochloride Gemzar ® Paclitaxel Taxol ® Paclitaxel, albumin bound Abraxane ® Pemetrexed Alimta ® Vinblastine sulfate – Vinorelbine tartrate Navelbine ®

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