NCCN Guidelines for Patients® | Lung Cancer - Non-Small Cell Lung Cancer

58 NCCN Guidelines for Patients ® : Lung Cancer – Non-Small Cell, 2018 5 Overview of cancer treatments Review Clinical trials have risks, too. Like any test or treatment, there may be side effects. Also, new tests or treatments may or may not improve your health. In fact, your health may worsen during a trial. Other downsides may include more hospital trips, paperwork, and extra costs for you. To join a clinical trial, you must meet the conditions of the study. Patients in a clinical trial are often alike in terms of their cancer and general health. Thus, if patients improve, it’s because of the treatment and not because of differences between them. To join, you’ll need to review and sign an informed consent form. This form describes the study in detail. The study’s risks and benefits should be described and may include others than those described above. Ask your treatment team if there is an open clinical trial that you can join. There may be clinical trials where you’re getting treatment or at other treatment centers nearby. You can also find clinical trials through the websites listed in Part 8. Review † † Lung surgery removes the tumor with some normal tissue around its edge. Lymph node surgery removes nodes with cancer and nodes that may have cancer. † † Radiofrequency ablation kills cancer cells using heat. † † Radiation therapy most often uses high-energy x-rays to treat lung cancer. † † Chemotherapy stops cancer cells from completing their life cycle so they can’t increase in number. † † Targeted therapy drugs stop cancer cells from getting food or signals to grow. † † Immunotherapy activates your body’s disease- fighting system to destroy cancer cells. † † Clinical trials give people access to new tests and treatments that otherwise can’t usually be received. These new tests and treatments may in time be approved by the FDA. I qualified for a clinical trial. Tumor has reduced in size by almost two- thirds and fluid cleared. Right now I’m doing great and my horizon has lengthened considerably. Grateful to be a “survivor.” – Fred Lung cancer survivor “

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