NCCN Guidelines for Patients® | Lung Cancer - Non-Small Cell Lung Cancer

Contents 7
How to use this book 8
1 Lung cancer basics 9
Lungs 10
A disease of cells 10
Cancer’s threat 12
Review 12
2 Assessing lung nodules 14
Team work 15
Your cancer risk 15
Signs of cancer 17
Repeat testing 18
Confirming cancer 21
Review 22
3 Cancer staging 23
Staging plan 24
TNM scores 24
The 5 stages 28
Review 28
4 Treatment planning 30
Medical history 31
Physical exam 31
Blood tests 32
Imaging tests 32
Airway tests 34
Lung function tests 35
Biopsy 35
Cancer lab tests 38
Review 41
5 Overview of cancer treatments 42
Surgery 43
Ablation 45
Radiation therapy 45
Chemotherapy 49
Targeted therapy 51
Immunotherapy 58
Clinical trials 59
Review 60
6 Treatment guide: Non-metastatic cancer 61
Overview 62
One primary tumor 64
Multiple primary tumors 80
Review 83
7 Treatment guide: Metastatic cancer 84
Overview 85
Overactive EGFR mutation 86
ALK gene rearrangement 87
ROS1 gene rearrangement 88
BRAF V600E mutation 89
PD-L1 positive 89
Biomarkers not present or unknown 90
Review 93
8 Making treatment decisions 94
It’s your choice 95
Questions to ask your doctors 95
What’s my diagnosis and prognosis? 96
What are my options? 97
What does each option require of me? 98
What is your experience? 99
Deciding between options 100
Websites 101
Review 101
Glossary 102
Dictionary 103
Acronyms 108
NCCN Panel Members for Non-Small Cell Lung Cancer 112
NCCN Member Institutions 113
Index 114

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