NCCN Guidelines for Patients® | Myelodysplastic Syndromes

18 NCCN Guidelines for Patients ® : Myelodysplastic Syndromes, 2018 2 Testing for MDS Bone marrow biopsy and aspiration Bone marrow biopsy and aspiration To confirm MDS, a sample of bone marrow must be removed from your body for testing. A bone marrow biopsy removes a small piece of solid bone along with a small amount of soft bone marrow inside the bone. A bone marrow aspiration removes a small amount of liquid bone marrow from inside the bone. Both tests are usually done at the same time on the back of the hip bone. You will likely lie on your side or your stomach during this test. See Figure 3. You may be offered a light sedative before the test. Your doctor will then clean the area of skin where the biopsy will be done. Next, you will receive local anesthesia to numb the area of skin and bone beneath. Once numb, a hollow needle will be inserted into your skin and then pushed into the bone to remove the liquid bone marrow with a syringe. Then, a wider needle will be inserted into the bone and twisted to remove the solid bone and marrow sample. You may feel some pain while the samples are being removed. Your skin may be bruised for a few days. The samples will be sent to a lab for testing. Figure 3 Bone marrow biopsy Doctors use a bone marrow biopsy and aspiration to remove a sample of bone marrow for testing. These tests are often done at the same time on the hip bone. Illustration Copyright © 2017 Nucleus Medical Media, All rights reserved.