NCCN Guidelines for Patients® | Melanoma

23 NCCN Guidelines for Patients ® : Melanoma, 2018 2  Tests for melanoma Tumor tissue tests Pathology results  Diagnosis. Whether melanoma is present and if so, the subtype, for example, superficial spreading melanoma.  Breslow thickness. How deep the tumor has grown into the skin, measured in millimeters.  Ulceration status. Whether or not the tumor’s top skin layer is present and intact (not ulcerated) or is broken or missing (ulcerated).  Dermal mitotic rate. A measure of how many melanoma cells are actually growing and dividing.  Peripheral margin status. Presence or absence of cancer cells in the normal- looking tissue around the sides of a tumor removed during initial biopsy or subsequent surgery.  Deep margin status. Presence or absence of cancer cells in the normal- looking tissue under a tumor removed during initial biopsy or subsequent surgery.  Microsatellitosis. Tiny tumors (satellites) that have spread to skin near the first melanoma tumor and can only be seen with a microscope.  Tumor location. The area of the body where the tumor is found.  Tumor regression. The presence of white blood cells called lymphocytes and scar-like changes that suggest a person’s immune system is attacking the skin melanoma.  Tumor-infiltrating lymphocytes. Presence or absence of white blood cells that may be present in primary melanomas.  Vertical growth phase. Direction of tumor growth is down into the skin.  Angiolymphatic invasion. Melanoma has grown into (invaded) lymph vessels or blood vessels.  Neurotropism. Melanoma cells are evident in or around nerves in the skin.  Histologic subtype. Classification based on microscopic features of the melanoma.

RkJQdWJsaXNoZXIy MTE3MTE1