49 NCCN Guidelines for Patients ® : Melanoma, 2018 4 Overview of melanoma treatments Clinical trials Complementary and alternative medicine CAM ( c omplementary and a lternative m edicine) is a group of treatments sometimes used by people with cancer. Many CAMs are being studied to see if they are truly helpful. • Complementary medicines are meant to be used alongside standard therapies, most often for relaxation, improving your health, or to prevent or reduce side effects. • Alternative medicine is treatment or techniques that are used instead of standard treatments such as chemotherapy or radiation. Some are sold as cures even though they haven’t been proven to work in clinical trials. Many cancer centers or local hospitals have complementary therapy programs that offer acupuncture, yoga, and other types of therapy. It’s important to tell your treatment team if you are using any complementary medicines, especially supplements, vitamins, or herbs. Some of these can interfere with your cancer treatment. For example, some supplements or herbs can increase or decrease levels of immunotherapy or chemotherapy drugs in your body. This may cause more side effects or make the treatment not work as well. For more information about CAM, ask your doctor and visit the websites in Part 6.