NCCN Guidelines for Patients
Malignant Pleural Mesothelioma, Version 1.2016
Testing for mesothelioma
For a thoracoscopic biopsy, also called a VATS
a small cut into your chest is needed. Next,
a thoracoscope is inserted through the cut. A
thoracoscope is a thin, tube-shaped instrument that
has a light and camera for viewing as well as a tool
to remove a tissue sample. A thoracoscopic biopsy
is done while you are under general anesthesia. This
surgery may cause some pain and swelling and will
leave a small scar.
SMRP blood test
Mesothelin-related peptides are made when
protein in the mesothelium breaks down. These
breakdown products are found in blood. People
with mesothelioma often have high levels of SMRP
eptide). This test
requires a sample of blood to be drawn from a vein
in your arm. The blood sample is then sent to the
lab to be tested. This test cannot be used alone to
diagnose mesothelioma; a biopsy is required.
Pleural effusion is the buildup of extra fuid
between the two layers of tissue lining the
Pleural thickening is widespread scarring of the
tissue around the lungs.
It is recommended that you get tested for
mesothelioma if you have had pleural effusion
more than once, have pleural thickening, or
Samples of pleural fluid and tissue must be
removed from your body and tested to confirm
if you have mesothelioma.
Imaging tests, like a CT scan, can show where
tumors are located.