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NCCN Guidelines for Patients



Malignant Pleural Mesothelioma, Version 1.2016


clinical trial

Research on a test or treatment to assess its safety or how

well it works.

computed tomography (CT) scan

A test that uses x-rays from many angles to make a picture

of the inside of the body.

conformal radiation therapy

Radiation beams are shaped to match the shape of the

cancer using imaging scans.


A dye put into your body to make clearer pictures during

imaging tests.

core biopsy

Removal of a larger sample of tissue using a wide needle to

be tested for disease.

crocidolite asbestos

Straight, brittle, needle-like asbestos fibers.

CT-guided core biopsy

Use of pictures from a CT (computed tomography) scan to

find the right spot to remove a sample of tissue or fluid to

test for disease.


To identify a disease.

diagnostic imaging specialist

A person trained to read pictures of the body made by

imaging tests.


A sheet of muscles below the ribs that helps a person to


electrocardiography (ECG) machine

A machine that measures the electrical activity of the heart

during exercise.

endobronchial ultrasound–guided fine-needle

aspiration (EBUS-FNA)

Removal of tissue with a needle at the end of a long, thin

tube guided down the main airway using imaging tests.

epithelioid subtype

The most common cell subtype of pleural mesothelioma;

cells of the epithelioid subtype are uniform and in organized


external beam radiation therapy (EBRT)

Radiation therapy (use of high-energy rays to destroy

cancer cells) received from a machine outside the body.

extrapleural pneumonectomy (EPP)

Surgery that removes the affected lung and all its tissue

lining, the sheet of muscles below, and sometimes the

tissue lining around the heart.

first-line treatment

The first set of treatments given to treat a disease.

gene mutation

Abnormal change in the instructions in cells for making and

controlling cells.

general anesthesia

A controlled loss of wakefulness from drugs.


The coded instructions in cells for making and controlling


histologic subtype

Grouping of cancer types based on differences in the

structure and organization of cells.


Itchy, swollen, and red skin caused by an allergic reaction—

action of the body’s natural defense against infection and

disease in response to a foreign substance in the body.

hospice care

Treatment focused on reducing symptoms caused by cancer

without treating the cancer itself.

imaging tests

Tests that take pictures of the inside of the body.


Redness, heat, pain, and swelling from injury or infection.

intensity-modulated radiation therapy (IMRT)

Radiation therapy (use of high-energy rays to destroy

cancer cells) that uses small beams of different strengths

based on the thickness of the tissue.


A thin, lighted tube with a lens for viewing and tools to

remove samples of tissue.


A type of surgery used to view the inside of the belly area

(abdomen) and take biopsy samples of organs and tissues.