NCCN Guidelines for Patients® | Malignant Pleural Mesothelioma - page 19

NCCN Guidelines for Patients
Malignant Pleural Mesothelioma, Version 1.2014
Testing for mesothelioma Tests to confirm mesothelioma
Abrams needle biopsy.
An Abrams needle biopsy
is like a core biopsy. However, it may or may not use
CT. An Abrams needle limits the amount of air that
enters tissue during a pleural biopsy.
Open biopsy.
An open biopsy requires a large
surgical cut into the chest. General anesthesia, a
controlled loss of wakefulness from drugs, is used.
The larger cut allows the surgeon to see into your
chest without any tools. Tissue samples are collected
with a surgical knife. For this biopsy, you will have to
stay in the hospital overnight.
Thoracoscopic biopsy.
For a thoracoscopic biopsy,
also called a VATS (
urgery) biopsy, a small cut into your chest is needed.
Next, a thoracoscope is inserted through the cut. A
thoracoscope is a thin, tube-shaped instrument that
has a light and camera for viewing as well as a tool
to remove a tissue sample. A thoracoscopic biopsy
is done while you are under general anesthesia. This
surgery may cause some pain and swelling and will
leave a small scar.
SMRP blood test
Mesothelin-related peptides are made when
protein in the mesothelium breaks down. These
breakdown products are found in blood. People with
mesothelioma often have high levels of SMRP. This
test requires a sample of blood to be drawn from a
vein in your arm. The blood sample is then sent to the
lab to be tested. This test cannot be used alone to
diagnose mesothelioma; a biopsy is required.
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