NCCN Guidelines for Patients® | Multiple Myeloma

19 NCCN Guidelines for Patients ® : Multiple Myeloma, 2019 2 Testing for myeloma Tissue tests Tissue tests To confirm if you have cancer, a sample of tissue or fluid must be removed from your body for testing. This is called a biopsy . A biopsy is generally a safe test and can often be done in about 30 minutes. The types of biopsies used for myeloma are described below. Bone marrow aspiration and biopsy A bone marrow biopsy removes a small piece of solid bone along with a small amount of soft bone marrow inside the bone. A bone marrow aspiration removes a small amount of liquid bone marrow from inside the bone. Often, both tests are done at the same time on the back of the hip bone. See Figure 6 . You may be given a light sedative before the test. Your doctor will then clean the area of skin where the biopsy will be done. Next, you will receive local anesthesia to numb the area of skin and bone beneath. Once numb, a hollow needle will be inserted into your skin and then pushed into the bone to remove the liquid bone marrow with a syringe. Then, a wider needle will be inserted into the bone and twisted to remove the solid bone and marrow sample. You will notice a pressure feeling as this is happening and you might feel some pain while the samples are being removed. Your skin may be bruised for a few days. The samples will be sent to a lab for testing. Figure 6 Bone marrow biopsy Doctors use a bone marrow biopsy and aspiration to remove a sample of bone marrow for testing. These tests are often done at the same time on the hip bone. Illustration Copyright © 2019 Nucleus Medical Media, All rights reserved.