62 NCCN Guidelines for Patients ® : Multiple Myeloma, 2018 Dictionary Dictionary active (symptomatic) myeloma When abnormal plasma cells (myeloma cells) have increased in the bone marrow and are causing symptoms such as kidney problems and bone damage. adjunctive treatment Medicine for symptoms of myeloma and side effects of myeloma treatment that is given at the same time as the main cancer treatment. albumin The main protein in blood plasma (yellowish part of blood). allogeneic stem cell transplant A treatment that destroys cells in the bone marrow with chemotherapy and then replaces them with healthy blood stem cells from another person. amyloid An abnormal protein that is formed by clumps of abnormal light chains and can damage organs. amyloidosis A health condition in which a protein called amyloid builds up in and damages organs. anemia A health condition in which the number of red blood cells is low. anesthesia Loss of feeling with or without loss of wakefulness caused by drugs. antibody A protein that is made by plasma cells, a type of white blood cell, to help fight off infections. Also called immunoglobulin. apheresis A procedure in which stem cells are removed from blood. asymptomatic Having no signs or symptoms of disease. autologous stem cell transplant A treatment that destroys cells in the bone marrow with chemotherapy and then replaces them with your own healthy blood stem cells. B-cell A type of white blood cell that turns into a plasma cell in response to germs. Bence Jones myeloma Condition in which myeloma cells make only free light chains and no complete M-proteins. Also called light chain myeloma. Bence Jones protein The shorter protein chain that is part of an M-protein. Also called a light chain. beta-2 microglobulin A small protein made by many cells, including white blood cells and myeloma cells. biopsy Removal of small amounts of tissue from the body to be tested for disease. bisphosphonates Drugs that help improve bone strength and prevent loss of bone mass. blood chemistry test A test that measures the amount of certain substances in the blood to check for signs of disease. blood clot A mass of blood that forms when blood platelets, proteins, and cells stick together. blood stem cell An immature cell from which all other types of blood cells are made. bloodstream Blood that flows throughout the body in small tubes called blood vessels. blood thinner A drug that thins out the blood to treat or reduce the risk of blood clots. blood urea nitrogen (BUN) A waste product made by the liver and filtered out of blood into urine by the kidneys.