67 NCCN Guidelines for Patients ® : Multiple Myeloma, 2018 Dictionary surgeon A doctor who’s an expert in operations to remove or repair a part of the body. surgery An operation to remove or repair a part of the body. symptom A physical or mental problem a person experiences that may indicate a certain disease or health condition. systemic therapy Drugs used to treat cancer cells throughout the body. tandem stem cell transplant Treatment in which a planned second round of high-dose chemotherapy and autologous stem cell transplant are given within 6 months of the first transplant. targeted therapy Treatment with drugs that target a specific or unique feature of cancer cells. tissue biopsy Removal of a small amount of tissue from the body to test for disease. total protein (urine) A test that measures the amount and type of protein in urine collected over a 24-hour period. transfusion Replacing lost blood with new blood. treatment response An outcome or improvement caused by treatment. tumor burden The amount or extent of cancer in the body. U.S. Food and Drug Administration (FDA) A federal government agency that regulates drugs and food. urine immunofixation electrophoresis (UIFE) A test that identifies the type of M-proteins in the urine. urine protein electrophoresis (UPEP) A test that shows the amount of M-proteins in the urine. vaccine A biological agent inserted into the body to prevent a disease. vein A small tube that carries blood to the heart from anywhere in the body. vertebrae The chain of 33 bones in the back that protect a vital group of nerves. vertebroplasty A procedure to strengthen bones in the spine with bone cement. white blood cell A type of blood cell that fights infection.