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NCCN Guidelines for Patients


Nausea and Vomiting, Version 1.2016



What are the types of nausea and vomiting?

Guide 2. Types of chemotherapy-induced nausea and vomiting


Details about the types


happens within a few minutes or

several hours of treatment.

• This type usually stops within the first 24 hours of treatment.

• The level of intensity of acute nausea and vomiting will go down

(peak) after 5

6 hours.

• This type is caused by a history of nausea and vomiting, the type

of cancer treatment, and amount given.

• Chemotherapy given for more than one day can cause this type.

• It usually occurs in woman young than 50 years of age who:

◦◦ Only drink small amounts of alcohol.

◦◦ Have a history of being sick from motion.

◦◦ Had morning sickness (nausea and vomiting) during



occurs more than 24 hours

after treatment is given.

• This type happens with chemotherapy drugs like cisplatin,

carboplatin, cyclophosphamide, and doxorubicin.

• For cisplatin, the vomiting gets to its highest intensity 48


hours after it is given. It can then last for 6

7 days.

• Chemotherapy given for more than one day can cause this type.


happens before the next

treatment is given.

• This type is based on a bad past experience when getting

treatment. You feel the bad experience all over again.

• Nausea is more common than vomiting with this type.

• Younger people with cancer are more likely to have this type


◦◦ They can be given more intense than usual (aggressive)


◦◦ It can be harder for younger people to control vomiting.


refers to nausea and

vomiting that happens despite trying to

prevent it with drugs.

• Anti-nausea and vomiting drugs called antiemetics are used to

treat this type.


refers to nausea and

vomiting that keeps happening even

when using drugs to stop or prevent it.

• The nausea and vomiting will keep happening with each

following treatment.

• The treatment for the nausea or vomiting is not working in the