NCCN Guidelines for Patients® | Diffuse Large B-cell Lymphoma

16 NCCN Guidelines for Patients ® : Diffuse Large B-cell Lymphoma, 2017 Physical exam Doctors should perform a physical exam along with taking a medical history. A physical exam is a study of your body for signs of disease. To start, your basic body functions will be measured. These functions include your temperature, blood pressure, and pulse and breathing (respiration) rate. Your weight will also be checked. During the exam, your doctor will listen to your lungs, heart, and gut. Your doctor will also look at and feel parts of your body. This is done to see if organs are of normal size, are soft or hard, or cause pain when touched. Cancer and other health conditions can cause organs to become enlarged and hard. Enlarged structures For DLBCL, there are certain parts of your body that should be checked. DLBCL is often found in lymph nodes. Thus, areas with lots of lymph nodes should be examined. High numbers of lymph nodes exist in the middle of your chest, neck, throat, armpit, groin, pelvis, and along your gut. The size of your spleen and liver should also be assessed. Performance status Results of your medical history and physical exam will be used to rate your performance status. Performance status is your ability to do daily activities. It is used by doctors to assess if you can undergo certain treatments. Blood tests Blood tests are used to learn if cancer treatment might be needed now. They are also used to find unknown diseases including those related to lymphoma. It’s important to treat all illnesses. Blood tests require a sample of your blood. Samples of blood can be removed with a blood draw. Before a blood draw, you might need to stop drinking and eating for several hours. A needle will be inserted into your vein to remove blood. Your blood sample will be sent to a lab for testing. Complete blood count with differential A CBC ( c omplete b lood c ount) measures parts of the blood. It is often done with a machine. Test results include counts of white blood cells, red blood cells, and platelets. Your blood counts may be low or high because of cancer or another health problem. It is an essential test that gives a picture of your overall health. There are several types of white blood cells. A differential counts the number of each type of cell. It also checks if the counts are in balance with each other. Your doctor can determine the cause of an abnormal white blood count from this test. Comprehensive metabolic panel Chemicals in your blood come from your liver, bone, and other organs. A comprehensive metabolic panel often includes tests for up to 14 chemicals. The tests show if the levels of chemicals are too low or high. Abnormal levels can be caused by cancer or other health problems. LDH LDH ( l actate d e h ydrogenase) is a protein that is in most cells. It gets into your blood when a cell is damaged. Thus, a high level of LDH is a sign of cell damage. High levels can be caused by cancer or other health problems. If related to lymphoma, high 2 Treatment planning Physical exam | Blood tests