NCCN Guidelines for Patients® | Diffuse Large B-cell Lymphoma

28 NCCN Guidelines for Patients ® : Diffuse Large B-cell Lymphoma, 2017 3 Overview of cancer treatments Chemotherapy What to expect Chemotherapy used to treat DLBCL is listed in Guide 2 . Most are liquids that are slowly injected into a vein. Some are a pill that is swallowed. By any method, the drugs travel in your bloodstream to treat cancer throughout your body. Doctors use the term “systemic” when talking about a cancer treatment for the whole body. Chemotherapy is given in cycles of treatment days followed by days of rest. This allows your body to recover before the next cycle. Cycles vary in length depending on which drugs are used. Often, a cycle is 2 to 4 weeks long. If you will have chemotherapy, ask your doctor how many cycles will be given. Also ask how many days of treatment there are within a cycle. Chemotherapy may consist of one or more drugs. When only one drug is used, it is called a single agent. However, not all drugs work the same way, so often more than one drug is used. A combination regimen is the use of two or more chemotherapy drugs. A steroid, immunotherapy, or both are often added to chemotherapy. Side effects of chemotherapy Side effects are unhealthy or unpleasant physical or emotional responses to treatment. They differ among Guide 2. Chemotherapy Generic (chemical) name Brand name (sold as) Bendamustine hydrochloride Treanda ® , Bendeka™ Carboplatin – Cisplatin Platinol ® Cyclophosphamide – Cytarabine Cytosar-U ® Doxorubicin hydrochloride – Doxorubicin hydrochloride, Liposome injection Doxil ® Etoposide; Etoposide phosphate Etopophos ® Preservative Free Gemcitabine hydrochloride Gemzar ® Ifosfamide – Methotrexate – Mitoxantrone hydrochloride Novantrone ® Oxaliplatin Eloxatin ® Procarbazine hydrochloride Matulane ® Vincristine sulfate – Vinorelbine Navelbine ®

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