NCCN Guidelines for Patients® | Mantle Cell Lymphoma

17 NCCN Guidelines for Patients ® : Mantle Cell Lymphoma, 2019 2  Treatment planning Physical exam | Blood tests Physical exam A physical exam is a study of your body. It is done to look for signs of disease. It is also used to help assess what treatments may be options. To start, your basic body functions will be measured. These functions include your temperature, blood pressure, and pulse and breathing rate. Your weight will also be checked. Your doctor will listen to your lungs, heart, and gut. He or she will also assess your eyes, skin, nose, ears, and mouth. Your doctor will feel parts of your body. This is done to see if organs are of normal size, are soft or hard, or cause pain when touched. Cancer and other health conditions can cause organs to become enlarged and hard. Enlarged structures The size of certain parts of your body should be checked. MCL is often found in lymph nodes. Thus, areas with lots of lymph nodes should be examined. High numbers of lymph nodes exist in the middle of your chest, neck, throat, armpit, groin, pelvis, and along your gut. Other parts of your body that should be checked include your spleen and liver. Performance status Your doctor will also rate your performance status. Performance status is your ability to do daily activities. It is used by doctors to assess if you can have certain treatments. Blood tests Doctors test blood to look for signs of disease. Blood tests are also used to learn if cancer treatment is needed now. Blood tests require a sample of your blood. Blood samples can be removed with a blood draw. Blood draw Some blood draws require no eating and drinking for hours. Your doctor will say if you can eat or drink. Blood samples will be removed from a vein with a needle. CBC with differential A CBC (complete blood count) measures parts of the blood. Test results include counts of white blood cells, red blood cells, and platelets. Cancer and other health problems can cause low or high counts. There are several types of white blood cells. A differential counts the number of each type of cell. It also checks if the counts are in balance with each other. Comprehensive metabolic panel Chemicals in your blood come from your liver, bone, and other organs. A comprehensive metabolic panel often includes tests for up to 14 chemicals. The tests show if the levels of chemicals are too low or high. Abnormal levels can be caused by cancer or other health problems. LDH LDH (lactate dehydrogenase) is a protein that is in most cells. It gets into your blood when a cell is damaged. Thus, a high level of LDH is a sign of cell damage. High levels can be caused by a fast- growing cancer or other health problems. Beta-2 microglobulin Beta-2 microglobulin is a small protein found on most cells. It is released by cells into the blood, especially