NCCN Guidelines for Patients® | Mantle Cell Lymphoma

29 NCCN Guidelines for Patients ® : Mantle Cell Lymphoma, 2017 3 Overview of cancer treatments Steroids agent. However, not all drugs work the same way, so often more than one drug is used. A combination regimen is the use of two or more chemotherapy drugs. A steroid, immunotherapy, or both are often added to chemotherapy. Side effects of chemotherapy Side effects are unhealthy or unpleasant physical or emotional responses to treatment. They differ among people. Some people have many side effects. Other people have few. Some side effects can be very serious. Others can be unpleasant but not serious. Side effects of chemotherapy depend on multiple factors. These factors include the drug type, amount taken, length of treatment, and the person. In general, side effects are caused by the death of fast- growing cells. Fast-growing cells are found in the hair follicles, gut, mouth, and blood. Death of these cells can cause low blood cell counts, not feeling hungry, nausea, vomiting, diarrhea, hair loss, and mouth sores. Lung damage may also occur at the time of treatment. Most side effects appear shortly after treatment starts and will stop after treatment. However, other side effects are long-term or may appear years later. Late side effects include another type of cancer, heart disease, low levels of thyroid hormones (hypothyroidism), and problems having babies (infertility). Not all side effects of chemotherapy are listed here. Please ask your treatment team for a complete list of common and rare side effects. If a side effect bothers you, tell your treatment team. There may be ways to help you feel better. There are also ways to prevent some side effects. Steroids Steroid is the short name for corticosteroid. It is a type of drug that is often used to relieve inflammation. Steroids also are toxic to lymphoma cells. They have strong anti-cancer effects. The steroids used to treat mantle cell lymphoma are listed in Guide 3 . Steroids are a part of some chemotherapy regimens. They are often given on the same days as chemotherapy but only for a few days or a week. Prednisone is made in pill form but dexamethasone and methylprednisolone are made both as a liquid to be injected or a pill to be swallowed. Most side effects of steroids fade away once the drugs are stopped. Common side effects include feeling hungry, upset stomach, and mood changes. You may have trouble sleeping. Wounds may be slow to heal. Swelling of ankles, feet, or hands is also common. Guide 3. Steroids Generic (chemical) name Brand name (sold as) Dexamethasone – Methylprednisolone; Methylprednisolone acetate; Methylprednisolone sodium succinate A-Methapred Depo-Medrol ® Medrol ® Solu-Medrol ® Prednisone –