NCCN Guidelines for Patients® | Mantle Cell Lymphoma

40 NCCN Guidelines for Patients ® : Mantle Cell Lymphoma, 2017 Follow-up care Guide 5 lists follow-up care for when there are no signs of cancer after treatment. This care may include a medical history, physical exam, imaging, and blood tests. A test schedule is listed in the Guide. However, these tests may be done whenever there are signs or symptoms of cancer. A biopsy is often needed to confirm there’s cancer. If the cancer returns (relapse), read Guide 6 for options. Second-line treatment Guide 6 lists options for second-line treatment. These options are used if first-treatment didn’t work. They are also used if the lymphoma reappears on tests. Options are based on your prior treatment. Prior immunotherapy ± radiation therapy You may have three options. One option is a clinical trial of new drugs or of a stem cell transplant. The second option is radiation therapy if you didn’t receive it before. The third option is a drug regimen listed in the Guide, or sometimes a regimen for diffuse large B-cell lymphoma is tried. Prior radiation therapy only Your first-line treatment may have consisted only of radiation therapy. In this case, you may be able to join a clinical trial. The other option is immunotherapy. Read Guide 7 for options. 4 Treatment guide Stage I and limited stage II