NCCN Guidelines for Patients
Mycosis Fungoides, Version 1.2016
Overview of cancer treatments Review
• Steroids have anti-cancer effects and are
often applied directly to skin lesions.
• Retinoids stop some types of cancer cells
from growing. Some retinoids are applied
directly to the skin while others are pills that
can treat cancer anywhere in the body.
• HDAC inhibitors enter cancer cells and turn
genes back on to cause cell death.
• Monoclonal antibodies for mycosis fungoides
attach to the lymphoma cells to 1) trigger an
attack from your immune system, or 2) deliver
• Immunotherapy for mycosis fungoides
includes medicines that are human-made
copies of molecules from your immune
system. Another medicine triggers your body
to make these molecules.
• Chemotherapy stops the life cycle of cancer
• Electron radiation therapy treats skin lesions
without much, if any, damage to underlying
tissue. There are two approaches—local and
total skin electron beam therapy.
• Phototherapy uses ultraviolet radiation to treat
local skin lesions.
• Extracorporeal photopheresis uses ultraviolet
radiation to treat cancer throughout the body.
• An allogeneic transplant suppresses your
immune system then transfuses donor stem
cells that will attack cancer cells.
• Clinical trials give people access to new tests
and treatments that otherwise can’t usually
be received. These new tests and treatments
may be approved, in time, by the FDA.