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NCCN Guidelines for Patients


Mycosis Fungoides, Version 1.2016



Genetic counseling | Treatment


Treatment guide

Stage III treatment

Chart 4.4.2

lists options for second-line treatment

of stage III cancers. Combination treatment is one

option. It may consist of skin and systemic treatment.

Otherwise, it may consist of two systemic treatments.

Specific regimens of combination treatment are listed

in the chart. A second option for second-line treatment

is a clinical trial.

Start treatment again if the cancer was fully treated

but came back as stage III. People often have good

results with the same treatment. If a new treatment

will be received, the choice of which treatment will be

partly based on how much of your skin has lesions. If

one or two courses of first-line treatment didn’t work,

try another treatment listed in the chart.

You may have already tried multiple courses of

first-line treatment without much change. Despite

treatment, the cancer may be worse. In either case,

options are listed in Chart 4.4.3

Chart 4.4.3

lists options for third-line treatment

of stage III cancers. There are four options. You

may be able to join a clinical trial. The second

option is systemic treatment. The third option is

to take alemtuzumab. The fourth option listed is a

nonmyeloblative allogeneic stem cell transplant.