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NCCN Guidelines for Patients


Peripheral T-cell Lymphoma, Version 1.2016


Treatment guide

Angioimmunoblastic T-cell lymphoma

Chart 4.3.3

lists second-line options that do include

a stem cell transplant. Second-line treatment is

received when first-line treatment didn’t work or the

cancer came back. A clinical trial is the preferred


The aim of the second option is to undergo a stem

cell transplant. The second option starts with treating

the cancer with cancer drugs. Regimens are listed

in the chart. The results of this treatment will be

assessed with tests.

There are three options if testing finds no signs of

cancer or the cancer is smaller. The first option is

to join a clinical trial of additional drug treatment

or of a stem cell transplant. The second and third

options are an autologous and allogeneic stem cell

transplant outside a clinical trial. Before or after the

chemotherapy portion of the transplant, you may

receive radiation therapy. More research is needed to

learn about the outcomes of these transplants.

If the cancer looks the same or worse after drug

treatment, there are 3 treatment options. The first

option is to join a clinical trial. The second option is

to receive another second-line drug regimen that is

listed in the chart. The third option is supportive care,

which might include radiation therapy to reduce the

symptoms of cancer.