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59

NCCN Guidelines for Patients

®

:

Ovarian Cancer, Version 1.2017

5

Treatment guide

Follow-up after initial treatment

Guide 11. Treatment for ovarian cancer that has come back

Follow-up results Prior treatment Treatment options

Symptoms, imaging tests,

or rising CA-125 levels

signal that cancer

has come back

ª

• No prior chemotherapy • Surgical treatment with or without

chemotherapy

Clinical and/or radiographic

relapse

(symptoms and/or imaging

test results show signs that

cancer has come

back after a complete

response

ª

ª

ª

• Currently on

chemotherapy

(disease keeps growing)

• Clinical trial

and/or

• Best supportive care

and/or

• Start recurrence treatment

• Finished chemotherapy

<6 months ago

• Clinical trial

and/or

• Start recurrence treatment

and/or

• Best supportive care

• Finished chemotherapy

>6 months ago

Clinical and/or radiographic relapse:

Maybe more surgery, then

• Clinical trial

and/or

• Platinum-based chemotherapy for 6

cycles (preferred)

or

• Other recurrence treatment

and/or

• Best supportive care

Biochemical relapse

(increase in CA-125 levels

is the only sign that cancer

has come back)

ª

• Prior chemotherapy

• Clinical trial

or

• Delay recurrence treatment until

symptoms appear (clinical relapse)

or

• Start recurrence treatment now, this may

include platinum-based chemotherapy

or

• Best supportive care