NCCN Guidelines for Patients
Ovarian Cancer, Version 1.2017
Borderline epithelial tumors
Borderline epithelial tumors (LMP [low malignant potential]
Guide 17. Borderline epithelial tumors (LMP) with surgical staging
Results Adjuvant treatment options
No invasive implants
• Consider treatment for grade 1 (low-grade) serous epithelial carcinoma
This type of cancer is slow growing and may not
invade other tissue. An LMP tumor may be found
by chance during surgery or tests for another health
problem. Most often, it is diagnosed after surgery.
Surgery is also used as primary treatment for this
type of tumor.
There is more than one primary treatment option
for an LMP tumor. Your doctor will consider more
than one factor when deciding on treatment. First,
surgical staging will be done to assess the extent of
disease. Second, your doctor will check whether or
not invasive implants were found. Tumor cells that
spread and grow on the surface of nearby organs are
called noninvasive implants. The tumor cells rarely
grow into (invade) tissue—called invasive implants.
Lastly, he or she will factor in whether or not you
want to have babies after treatment. Fertility-sparing
surgery is always an option for an LMP tumor.
Observation with follow-up tests is an option for all
See Guide 17.
If surgical staging was complete and no invasive
implants were found, then this is the only option
recommended. If invasive implants were found, a
second option is to receive chemotherapy. If surgical
staging was not complete, then another option is to
have more surgery. This may include fertility-sparing
surgery and surgical staging procedures.
For surgical staging, biopsy samples will be taken
from the tumor and nearby tissues. The omentum
and nearby lymph nodes may also be removed. If
you don’t want to have babies, then you may have
completion surgery. Completion surgery removes the
remaining ovary (or ovaries), fallopian tubes, uterus,
omentum, and any tumor cells found on nearby
tissue. In some cases, nearby lymph nodes may also
If invasive implants were found, then surgery may
be followed by chemotherapy. If no invasive implants
were found, then no other treatment is recommended
after either surgery. Instead, you will begin
observation with follow-up tests.