NCCN Guidelines for Patients
Pancreatic Cancer, Version 1.2017
If the first biopsy doesn’t confirm pancreatic cancer,
then the next step is to treat symptoms such as
jaundice as described in the previous paragraph.
However, when placing the biliary stent, your doctor
may also take samples (called brushings) of the duct
for testing. Then, at least two more biopsies should
be done to try to confirm pancreatic cancer. There is
more than one type of biopsy that can be used, but
EUS-FNA with or without a core biopsy is preferred.
A core biopsy would remove a larger sample of
tissue with a wide, hollow needle to further test for
If another type of cancer is found on biopsy, you will
seek treatment for that type of cancer. Your doctor
may refer to the NCCN treatment guideline for the
type of cancer confirmed on biopsy.
After confirming pancreatic cancer with a biopsy and
treating jaundice, see Guide 14 for first-line treatment
Treatment guide Locally advanced unresectable pancreatic cancer