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NCCN Guidelines for Patients



Pancreatic Cancer, Version 1.2017

If the first biopsy doesn’t confirm pancreatic cancer,

then the next step is to treat symptoms such as

jaundice as described in the previous paragraph.

However, when placing the biliary stent, your doctor

may also take samples (called brushings) of the duct

for testing. Then, at least two more biopsies should

be done to try to confirm pancreatic cancer. There is

more than one type of biopsy that can be used, but

EUS-FNA with or without a core biopsy is preferred.

A core biopsy would remove a larger sample of

tissue with a wide, hollow needle to further test for


If another type of cancer is found on biopsy, you will

seek treatment for that type of cancer. Your doctor

may refer to the NCCN treatment guideline for the

type of cancer confirmed on biopsy.

Next steps

After confirming pancreatic cancer with a biopsy and

treating jaundice, see Guide 14 for first-line treatment



Treatment guide Locally advanced unresectable pancreatic cancer