NCCN Guidelines for Patients® | Pancreatic Cancer - page 72

NCCN Guidelines for Patients
Pancreatic Cancer, Version 1.2014
Treatment guide
Metastatic pancreatic cancer
Chart 5.5.2
shows the second-line treatment options
that are recommended for metastatic pancreatic
cancer. Second-line treatment is the next set of
treatments given when the first or previous treatments
failed to stop cancer growth.
Health status rating
Which treatment is recommended for you depends
on your health status rating, also called performance
status. Your health status is a rating by your doctor
based on your overall health, cancer symptoms, and
ability to do daily activities. Your doctor will rate your
health status again after first-line treatment to decide
which option is best to give you next.
Good health status means that your overall health is
good. You’re able to continue doing all of your regular
daily activities very well. You also have very few or
very mild symptoms of the cancer and you’re able to
eat well. Poor health status means that your overall
health is poor. You aren’t able to do your regular daily
activities well. The number and/or severity of cancer
symptoms is increased.
Your health status rating is a very important factor
when choosing the best treatment for you. This
is because healthier patients are able to tolerate
treatments with higher risks of side effects. Certain
treatments and drug combinations have a higher risk
of severe, even lethal, side effects. Your doctor should
explain all of the risks and possible side effects of the
treatments you receive.
Health status rating
Second-line treatment
Good health status
(Overall health is good,
able to do all normal
daily activities well, few
cancer symptoms, good
pain control, and good
Poor health status
(Overall health is poor,
unable to do normal
daily activities well, and
severe or uncontrolled
cancer symptoms)
Clinical trial (preferred),
Gemcitabine-based therapy, or
Radiation therapy for severe
pain resistant to medication
Palliative and best
supportive care, or
Palliative and best supportive care
Clinical trial
Chart 5.5.2 Second-line treatment
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