Table of Contents Table of Contents
Previous Page  84 / 112 Next Page
Information
Show Menu
Previous Page 84 / 112 Next Page
Page Background

82

NCCN Guidelines for Patients

®

Prostate Cancer, Version 1.2016

Guide 21. Treatment for M1 stage

First-line immunotherapy

Treatment conditions

• Sipuleucel-T is an option if these statements describe you:

◦◦ The cancer is causing few or no symptoms,

◦◦ There are no liver metastases,

◦◦ You are expected to live more than 6 months, and

◦◦ You are in good health other than having cancer

Other first-line treatment

Options if no metastases in internal organs

Options if metastases in internal organs

• Abiraterone acetate with prednisone

• Docetaxel with prednisone

• Docetaxel with prednisone

• Enzalutamide

• Enzalutamide

• Abiraterone acetate with prednisone

• Radium-223 for bone metastases causing

symptoms

• Alternative chemotherapy (mitoxantrone)

• Clinical trial

• Clinical trial

• Secondary hormone therapy

◦◦ Antiandrogen

◦◦ Antiandrogen withdrawal

◦◦ Ketoconazole ± hydrocortisone

◦◦ Corticosteroids

• Secondary hormone therapy

◦◦ Antiandrogen

◦◦ Antiandrogen withdrawal

◦◦ Ketoconazole ± hydrocortisone

◦◦ Corticosteroids

7

Treatment guide: Systemic treatment

Castration-recurrent prostate cancer