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NCCN Guidelines for Patients


Prostate Cancer, Version 1.2016


• Advanced disease is often first treated with ADT.

• CRPC is prostate cancer that grows even though

testosterone is at very low levels.

• A clinical trial, observation, and secondary

hormone therapy are options for CRPC without


• Newer treatments for CRPC with metastases

include sipuleucel-T, abiraterone acetate,

enzalutamide, and radium-223. Chemotherapy

with hormone therapy, clinical trials, and secondary

hormone therapy are other options.

• All men with CRPC should receive supportive care.


Treatment guide: Systemic treatment

Castration-recurrent prostate cancer