NCCN Guidelines for Patients® | Prostate Cancer

How to use this book 8
1 9
Prostate cancer basics 9
Explains how prostate cancer starts and how it spreads. 9
The prostate 10
A disease of cells 10
Cancer’s threat 12
Review 13
2 14
Cancer staging 14
Describes how doctors rate the growth of prostate cancer. 14
Prostate-specific antigen 15
Digital rectal exam 16
Imaging tests 17
Prostate biopsy 19
Gleason score 20
TNM scores 23
Review 25
3 26
Treatment planning 26
Describes how doctors plan your treatment. 26
Life expectancy 27
Risk assessment 27
Imaging for metastases 28
Review 31
4 32
Overview of cancer treatments 32
Describes the treatments used to cure or control prostate cancer. 32
Active surveillance 33
Surgical treatment 33
Radiation therapy 37
Cryosurgery 40
High intensity focused ultrasound 40
Hormone therapy 41
Immunotherapy 44
Chemotherapy 44
Radiopharmaceuticals 45
Clinical trials 46
Understudied treatments 48
Review 48
5 49
Initial treatment 49
Presents the options when treating prostate cancer for the first time. 49
Very low risk 51
Low risk 53
Favorable intermediate risk 56
Unfavorable intermediate risk 58
High risk or very high risk 60
Regional cancer 62
Review 63
6 64
Treatment monitoring 64
Presents tests that check treatment results and options if local treatment fails. 64
Reducing ADT risks 65
Initial treatment results 67
Treatment after prostatectomy 68
Treatment after radiation therapy 70
Review 71
7 72
Treatment guide: Systemic treatment 72
Presents options that control the growth of advanced cancer 72
Castration-naïve prostate cancer 73
Castration-resistant prostate cancer 76
Review 82
8 83
Making treatment decisions 83
Offers tips for choosing the best treatment. 83
It’s your choice 84
Questions to ask your doctors 84
Deciding between options 89
Websites 90
Decision Aids 90
Review 90
NCCN Panel Members for Prostate Cancer 97
NCCN Member Institutions 98
Dictionary 92
Acronyms 96
Dictionary 92
Acronyms 96
Index 100

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