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NCCN QUICK GUIDE
Brain Cancer – Gliomas, Version 1.2016
What are the treatment options for grade III
oligodendrogliomas and oligoastrocytomas?
Surgery is often used to confirm the presence of and to treat grade III gliomas. If the
tumor is fully removed, chemotherapy wafers may be placed into your brain at the end of
surgery. MRI is often needed to assess how much of the cancer was removed.52
Treatment options after surgery are based on your health and sometimes cell features.
If healthy enough, you may be treated with radiation and chemotherapy if the cells
have a 1p19q codeletion. If there’s no codeletion, your options may include radiation,
chemotherapy, or both. If your health is limited, you may receive a short or normal course
of radiation therapy, chemotherapy, or supportive care.54
MRI scans are needed on a regular basis to track treatment results.54
If a grade III cancer returns, treatment options depend on where the cancer is and its
extent. Surgery may be an option followed by chemotherapy, radiation, or supportive care.
When surgical treatment isn’t an option, other options include chemotherapy, surgery for
symptoms, and supportive care.56
How do you decide between options?
Ask your doctors many questions. Also, you could get a second opinion, attend support
groups, and compare pros and cons.69
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