NCCN Quick Guide™ | Lung Cancer - Non-Small Cell Lung Cancer - Treatment for metastatic cancer

NCCN Quick Guide™ | Lung Cancer - Non-Small Cell Lung Cancer - Treatment for metastatic cancer

1 of 2 NCCN QUICK GUIDE tm Lung Cancer, 2018 This NCCNQUICK GUIDE tm sheet summarizes key points from the complete NCCN Guidelines for Patients ® : Lung Cancer . T hese guidelines explain which tests and treatments are recommended by experts in cancer. To view and download the guidelines, visit NCC N.or g/ patients or, to order printed copies, visit Amazon.com What are metastatic cancers? These cancers have spread to distant sites. They include stage IV cancers. They also include earlier stages that have spread to distant sites. 60 What are treatment options for known mutations? EGFR mutation „„ Erlotinib 84 „„ Afatinib „„ Gefitinib „„ Osimertinib „„ Treatment for histologic type (see page 2) ALK gene rearrangement „„ Alectinib (preferred) 85 „„ Crizotinib „„ Ceritinib „„ Brigatinib „„ Treatment for histologic type (see page 2) ROS1 gene rearrangement „„ Crizotinib (preferred) 86 „„ Ceritinib „„ Treatment for histologic type (see page 2) BRAF V600E mutation „„ Dabrafenib + trametinib 87 „„ Treatment for histologic type PD-L1 positive „„ Pembrolizumab 87 „„ Treatment for histologic type (see page 2) NCCN Guidelines for Patients ® Page Number Ü NCCN GUIDELINES FOR PATIENTS ® NCCN QUICK GUIDE tm Lung Cancer Non-Small Cell Lung Cancer Treatment for metastatic cancers 2018

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