NCCN Quick Guide™ | Lung Cancer - Non-Small Cell Lung Cancer - Treatment for non-metastatic cancers

2 of 2 NCCN QUICK GUIDE tm Lung Cancer, 2018 PAT-N-1025-1017 Options for stage II continued Superior sulcus tumor „„ Chemoradiation then surgery then chemotherapy 68 „„ Chemoradiation alone Growth of tumor into other tissues (Invasion) „„ Surgery to remove the lung tumor and lymph nodes „„ Afterward, chemotherapy if chances are low that cancer remains. If high, surgery with chemotherapy or only chemoradiation. 68 „„ Chemoradiation or chemotherapy followed by surgery „„ Another surgery if not all of the cancer was removed „„ Chemoradiation alone What are the treatment options for stage III? N0 or N1 disease – No invasion „„ Surgery to remove the lung tumor and lymph nodes „„ Afterward, chemotherapy if chances are low that cancer remains. If high, you may have chemoradiation. 72 „„ Chemoradiation followed by durvalumab N0 or N1 disease – Superior sulcus tumor „„ Chemoradiation then surgery then chemotherapy 73 „„ Chemoradiation then more chemotherapy then durvalumab „„ Chemoradiation alone then durvalumab N0 or N1 disease – Invasion „„ Surgery to remove the lung tumor and lymph nodes „„ Afterward, chemotherapy if chances are low that cancer remains. If high, surgery with chemotherapy or only chemoradiation . 74 „„ Chemoradiation followed by surgery „„ Another surgery if not all of the cancer was removed „„ Chemoradiation alone then durvalumab N2 disease „„ Chemoradiation alone then durvalumab 75 „„ Chemotherapy with or without radiation therapy then surgery „„ Afterward, radiation (if none prior) with or without chemotherapy N3 disease „„ Chemoradiation alone then durvalumab 76 NCCN Guidelines for Patients ® Page Number Ü NCCN.org/patients - for Patients | NCCN.org - for Clinicians The NCCN QUICK GUIDE tm series and NCCN Guidelines for Patients ® are supported by charitable donations made to the NCCN Foundation ® . For more details and the full library of patient and caregiver resources, visit NCCN.org/patients. DONATE NOW NCCNFoundation.org/Donate

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