NCCN Quick Guide™ | Multiple Myeloma

1 of 2 NCCN QUICK GUIDE tm Multiple Myeloma, 2018 This NCCNQUICK GUIDE tm sheet summarizes key points from the complet e NCCN Guidelines for Patients ® : Multiple Myeloma . T hese guidelines explain which tests and treatments are recommended by experts in cancer. To view and download the guidelines, visit NCC N.or g/patients or, to order printed copies, visit What is multiple myeloma? Multiple myeloma is a cancer of white blood cells called plasma cells. It starts in the bone marrow—the soft tissue in the center of most bones where blood cells are made. 10 Myeloma can spread throughout bone marrow, causing much damage to bones and other organs. 10 Doctors use many types of tests to find and confirm (diagnose) multiple myeloma. 15 How do doctors classify myeloma to plan treatment? Doctors assess the extent of myeloma cells and severity of symptoms „„ A solitary plasmacytoma is when there is only one mass of myeloma cells in the body. 39 „„ Smoldering multiple myeloma is when there’s an increased number of myeloma cells in the bone marrow, but the cancer is not causing symptoms. „„ Active multiple myeloma is when there’s an increased number of myeloma cells in the bone marrow and the cancer is causing symptoms. What are the main (primary) treatment options for myeloma? Solitary plasmacytoma Radiation therapy ± surgery 40 Smoldering myeloma Observe at 3- to 6-month intervals or clinical trial 42 Active myeloma Myeloma therapy or bisphophonates and adjunctive treatment as needed 43 How will I know if treatment is working? „„ An outcome or improvement caused by treatment is called a treatment response. „„ Doctors use a number of follow-up tests to check for a treatment response. 46 NCCN Guidelines for Patients ® Page Number Ü NCCN GUIDELINES FOR PATIENTS ® NCCN QUICK GUIDE tm Multiple Myeloma 2018