2 of 2 NCCN QUICK GUIDE tm Diffuse Large B-cell Lymphoma, 2017 PAT-N-1016-0917 What are the treatment options? First-line treatment Immunochemotherapy is the first treatment received 38 Treatment results will be assessed with PET/CT scan. The next treatment depends on the cancer stage and treatment results Finish immunochemotherapy Radiation therapy (common for stages I & II) Second-line treatment if immunochemotherapy didn’t work Follow-up care Get tested on a regular basis if first-line treatment worked An update of your health history An exam of your body Lab tests CT scan at times or as needed 42 Second-line treatment Immunochemotherapy then blood stem cell transplant Clinical trial Chemotherapy ± immunotherapy Targeted therapy Immunomodulator ± immunotherapy Immunotherapy Radiation therapy Best supportive care 44 What are some tips for making good treatment decisions? Ask your doctors many questions. Also, you could get a second opinion, attend support groups, and compare pros and cons. 47 NCCN Guidelines for Patients ® Page Number Ü NCCN.org - for Clinicians | NCCN.org/patients - for Patients DONATENOW nccnfoundation.org The NCCN QUICK GUIDE tm series and NCCN Guidelines for Patients ® are supported by charitable donations made to the NCCN Foundation ® . For more details and the full library of patient and caregiver resources, visit NCCN.org/patients.