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NCCN QUICK GUIDE

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Mycosis Fungoides, Version 1.2016

NCCN Guidelines

for Patients

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NCCN.org - For Clinicians

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NCCN.org/patients - For Patients

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What are my treatment options?

Stage IA

Since the extent of the skin lesions is small, skin treatments given right to

the lesions are often first used. Second-line treatments include a whole-

body treatment with or without skin treatment, electron beam therapy to all

your skin, and clinical trials.

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Stage IB

and IIA

Skin treatments that target a large area of skin are often first used. Local

skin treatments may be added. Second-line treatments include clinical

trials, whole-body treatment, and certain combinations of two treatments.

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Stage IIB

If lesions cover less than 10% of your skin, tumors are treated with

radiation therapy and other lesions with other skin treatments. Second-

line treatments include electron beam therapy of all your skin, whole-body

treatment with or without a skin treatment, and certain combinations of two

treatments.

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If lesions cover more than 10% of your skin, electron beam therapy of

all your skin, whole-body treatment with or without a skin treatment, and

certain combinations of two treatments are first used for treatment. Second-

line treatments include multi-agent chemotherapy, allogeneic stem cell

transplant, and clinical trials.

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Stage III

Treatment depends on whether there is blood involvement. If not, skin

treatments may be received. Whole-body treatment with or without skin

treatment is used if there is blood involvement. Second-line treatments

include certain combinations of two treatments. Third-line treatments

include clinical trials, whole-body treatments, alemtuzumab, and

nonmyeloablative allogeneic stem cell transplant.

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Stage IV

One or more whole-body treatments are first used. Radiation therapy may

be added. The next option is to join a clinical trial.

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How do I decide between options?

Ask your doctors many questions. Also, you could get a second opinion, attend support groups,

and compare pros and cons.

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