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NCCN QUICK GUIDE

tm

Waldenström’s Macroglobulinemia, Version 1.2017

This NCCNQUICK GUIDE

tm

sheet summarizes key points from the complete

NCCN Guidelines for Patients ® : Waldenström’s Macroglobulinemia/Lymphoplasmacytic Lymphoma.

These

guidelines explain which tests and treatments are recommended by experts in cancer. To view

and download the guidelines, visit

NCCN.org/patients

or, to order printed copies, visit

Amazon. com.

What is Waldenström’s macroglobulinemia?

W

aldenström’s

m

acroglobulinemia (WM) is a type of

n

on-

H

odgkin’s

l

ymphoma (NHL). It

is a rare type of lymphoma. Lymphoma is a type of cancer that starts in the cells of the

immune system.

8

WM cells share similarities with both plasma cells (multiple myeloma) and lymphocytes

(lymphoma).

11

For reasons that are not clear, most Waldenström tumor cells make a type of antibody or

immunoglobulin called IgM (

i

mmuno

g

lobulin

M

).

11

What tests may I need before treatment?

Medical history and

physical exam

Two basic tools of diagnosis are when your doctor takes your

medical history and does an exam of your body.

15

Blood tests

Your doctors will order a complete blood count, comprehensive

metabolic panel, and test for IgM in the blood.

15

Imaging tests

A CT of the chest, abdomen, and pelvis is the most common

imaging test for WM.

17

Biopsy

Samples of tissue or fluid must be removed from your body and

be tested to diagnose cancer.

18

Why is treatment given?

For people with WM, treatment is given to control disease and limit harm to your organs.

If you are not having symptoms, you may not be treated right away.

20

NCCN Guidelines

for Patients

®

Page Number

Ü

Version 1.2017

NCCN

GUIDELINES

FOR PATIENTS

®

NCCN QUICK GUIDE

tm

Waldenström’s Macroglobulinemia

/

Lymphoplasmacytic Lymphoma