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NCCN QUICK GUIDE
Waldenström’s Macroglobulinemia, Version 1.2017
What are my options?
Your doctor will watch you closely to see if the cancer is
growing. You will both decide when and if you should start
Plasmapheresis is a process that removes IgM from the
Chemotherapy, or chemo, is a main systemic cancer treatment.
Systemic treatment travels throughout the body.23
Steroids are a type of drug that is often used to relieve
inflammation. Steroids also are toxic to lymphoma cells and
therefore have strong anti-cancer effects.25
Targeted therapies are drugs that sometimes can directly kill
cancer cells. They can be used alone or combined with other
Immunomodulators are drugs that modify different parts of your
immune system. The exact function of these drugs is not known.28
Stem cell transplant
A stem cell transplant replaces damaged or destroyed stem cells
with healthy stem cells, which form new marrow and blood cells.29
A clinical trial is a type of research study that people chose to
take part in.30
When is treatment given?
The first treatment options for WM are called primary treatment.
You should get this treatment if you have symptoms of WM.36
Treatment for WM that didn’t respond to (refractory) or reappears
(relapsed) after the first treatment.39
How do I decide between my options?
Ask your doctors many questions. Also, you could get a second opinion, attend support
groups, and compare the benefits and risks.42
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